Programmed Death Ligand 1 (PD-L1) Expression in Primary Angiosarcoma

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Programmed Death Ligand 1 (PD-L1) Expression in Primary Angiosarcoma

Angiosarcomas are rare malignant endothelial-cell tumors of vascular or lymphatic origin, and are among the most aggressive subtypes of soft-tissue sarcomas. The prognosis is poor and treatment is challenging in many cases. PD-1/PD-L1 pathway plays a critical role in immune escape of tumor cells. Recent studies described that PD-L1 is widely expressed in various types of cancer, providing the b...

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Programmed death ligand 1 (PD-L1) expression and tumor infiltrating lymphocytes in glioblastoma Running title: PD-L1 expression in glioblastoma

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Prognostic value of programmed death-ligand 1 (PD-L1) expression in ovarian clear cell carcinoma

OBJECTIVE Programmed death-ligand 1 (PD-L1) was expressed in various tumors and antibodies targeting its receptor programmed cell death-1 (PD-1) are emerging cancer therapeutics. This study was designed to evaluate the expression of PD-L1 and its correlation with clinicopathologic features and clinical outcomes in ovarian clear cell carcinoma (OCCC). METHODS The PD-L1 expression was measured ...

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Programmed death-ligand 1 (PD-L1) expression in various tumor types

Background Programmed cell death-1 (PD-1) is a co-inhibitory receptor expressed on lymphoid and non-lymphoidderived cells that negatively regulates peripheral T-cell responses. PD-L1, the major PD-1 ligand, is expressed on various tumors and is being investigated as a possible predictive marker for anti-PD-1 therapy. Few studies have determined PD-L1 expression across tumor types using a consis...

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Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors

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ژورنال

عنوان ژورنال: Journal of Cancer

سال: 2017

ISSN: 1837-9664

DOI: 10.7150/jca.19060